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Foundation Medicine Inc foundationone liquid cdx ngs
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
Foundationone Liquid Cdx Ngs, supplied by Foundation Medicine Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
Genoptix 5 Gene Panel, supplied by Genoptix Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Foundation Medicine Inc foundationone heme panel
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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Chem Impex International carboxyphenol ba
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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Genoptix Inc myeloid molecular profile
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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RainDance Technologies ngs assays raindance
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
Foundationone Liquid Cdx, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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AstraZeneca ltd koselugo (selumetinib
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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Neoplus inc foundationone assay
a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The <t>FoundationOne</t> liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.
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Image Search Results


a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The FoundationOne liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.

Journal: Case Reports in Oncology

Article Title: Utilizing Liquid Biopsy for Treatment Management in Bone-Dominant Metastatic Breast Cancer: A Case Report

doi: 10.1159/000526642

Figure Lengend Snippet: a The timeline of Patient 1. The second Guardant360 liquid biopsy on September 2021 revealed a PIK3CA E452K-targetable mutation. b The timeline of Patient 2. The FoundationOne liquid biopsy on January 2019 and the following tissue biopsy on January 2019 both revealed a PIK3CA E545K mutation. FAC, doxorubicin, cyclophosphamide, and fluorouracil; T, paclitaxel; OFS, ovarian function suppression; AI, aromatase inhibitor; SERD, selective estrogen receptor degrader.

Article Snippet: After another 4 years and multiple therapies, she underwent FoundationOne®Liquid CDx NGS testing (Foundation Medicine, Cambridge, MA, USA, https://www.foundationmedicine.com/ ), which identified PTEN I101N, ESR1 Y537N and D538G, CDH1 F810fs, and PIK3CA E545K mutations (Fig. ).

Techniques: Mutagenesis

a A FoundationOne®Liquid CDx testing that was collected via blood draw on Patient 2. PTEN I101N, ESR1 Y537N and D538G, CDH1 F810fs, and PIK3CA E545K mutations were found (Collection date December 19, 2018). b A FoundationOne®CDx testing from a tissue bone biopsy that was performed after academic center consultation. PTEN I101N, ESR1 Y537N, CDH1 F810fs, and PIK3CA E545K mutations, TMB-4Mut/Mb, and Microsatellite-stable were reported (collection date: January 21, 2019).

Journal: Case Reports in Oncology

Article Title: Utilizing Liquid Biopsy for Treatment Management in Bone-Dominant Metastatic Breast Cancer: A Case Report

doi: 10.1159/000526642

Figure Lengend Snippet: a A FoundationOne®Liquid CDx testing that was collected via blood draw on Patient 2. PTEN I101N, ESR1 Y537N and D538G, CDH1 F810fs, and PIK3CA E545K mutations were found (Collection date December 19, 2018). b A FoundationOne®CDx testing from a tissue bone biopsy that was performed after academic center consultation. PTEN I101N, ESR1 Y537N, CDH1 F810fs, and PIK3CA E545K mutations, TMB-4Mut/Mb, and Microsatellite-stable were reported (collection date: January 21, 2019).

Article Snippet: After another 4 years and multiple therapies, she underwent FoundationOne®Liquid CDx NGS testing (Foundation Medicine, Cambridge, MA, USA, https://www.foundationmedicine.com/ ), which identified PTEN I101N, ESR1 Y537N and D538G, CDH1 F810fs, and PIK3CA E545K mutations (Fig. ).

Techniques: